In vitro Toxicity Testing for Ex Vivo Primary Cells, Es and iPS-derived Cells and Cell lines

STEMGlo™-assays with Bioluminomics™ technology are suitable to measure toxicity on various cell types:

  • Hepatotoxicity
  • Neurotoxicity
  • Renal toxicity
  • Cardiotoxicity
  • Skin toxicity
  • Lung toxicity

STEMGlo™-Tox HT

Assays to measure potential toxicity using different cell types from a variety of mammalian species

CATALOG NO. DESCRIPTION STORAGE SIZE
KSG-T96-A-2
KSG-T96-A-4		 STEMGlo™-Tox HT for adherent cells -20°C 2 x 96-well kit
4 x 96-well kit
KSG-T96-NA-2
KSG-T96-NA-4		 STEMGlo™-Tox HT for non-adherent cells -20°C 2 x 96-well kit
4 x 96-well kit

STEMGlo™ PRT

Residual toxicity and sensitivity assays

When cells respond to cytotoxic agents, not all the cells may be inhibited or killed. The cells that are not affected are residual cells. When removed and re-plated, these cells may still be capable of proliferation. The residual dose response after secondary re-plating may indicate a shift to the left or right indicating a change in agent/drug sensitivity. Secondary re-plating also indicate the presence of stem cells from that tissue or organ.

CATALOG NO. DESCRIPTION STORAGE SIZE
KSG-PRT-A-2 STEMGlo™ PRT for adherent cells -20°C 2 x 96-well kit
KSG-PRT-NA-2 STEMGlo™ PRT for non-adherent cells -20°C 2 x 96-well kit

HepatoGlo™-Tox HT

Hepatotoxicity ATP bioluminescent assays

  • For incorporation of fresh of frozen primary or iPS-defived hepatocytes
  • HepatoGlo™ specialized growth medium
CATALOG NO. DESCRIPTION STORAGE SIZE
KHG-96-A-2 HepatoGlo™-Tox HT for adherent cells -20°C 2 x 96-well kit
KHG-96-NA-2 HepatoGlo™-Tox HT for non-adherent cells -20°C 2 x 96-well kit

STEMClone™

Clonal methylcellulose proliferation and differentiation assays

  • Manual colony enumeration AND standardized ATP bioluminescence
  • Based on the “classic” colony-forming cell (CFC)-assay
CATALOG NO. DESCRIPTION STORAGE SIZE
KSC-96-A-1
KSC-96-A-2
KSC-96-A-4		 STEMClone™
for primary stem cells and stem cell lines		 -20°C 1 x 96-well kit
2 x 96-well kit
4 x 96-well kit