01.09.2017

COMING SOON! Culture Media (cGMP) for Dendritic Cells

Monocyte-derived dendritic cells (Mo-DCs) have garnered much attention to develop effective strategies for therapeutic immunity against cancer. A recent study examined a new chemically defined & animal component free cultivation method to favorably support immunogenic applications of Mo-DC and highlights a potential role for lipids in programming the dendritic cells fate.

Results:

> Comparable yield of Mo-DCs
> Efficient differentiation, maturation, and maintanance of Mo-DC

Mo-DCs demonstrated an Th1 polarizing effect upon addition of several chemically-difined lipids (CDL)

These results exhibit a new CD, ACF cultivation method able to favorably support immunogenic applications of Mo-DC and highlights a potential role for lipids in programming DC fate.

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September 26 - October 01EUROTOX 2021 [virtual]